Top Molecular Pathology Testing Labs in South Texas
Molecular Testing – Finding the Genetic Drivers of Cancer
Molecular genetic testing has become a cornerstone in the diagnosis and management of cancer, particularly for identifying treatable or targetable mutations. This technology involves analyzing tumor DNA or RNA to detect specific genetic alterations that drive cancer growth.
Understanding these mutations allows for more precise classification of tumors and enables the use of targeted therapies designed to inhibit the molecular pathways involved in tumor progression. As a result, molecular testing supports the principles of personalized medicine and significantly improves clinical outcomes.
Key roles of molecular genetic testing in identifying treatable cancer mutations include:
- Rapid In-house detection of actionable mutations (e.g., EGFR, BRAF, KRAS, ALK, POLE) for targeted therapy selection
- Stratification of patients for immunotherapy based on biomarkers such as PD-L1, Claudin-18, FOLR1, HER2, or MSI (mismatch repair) status
- Prognostic insights that guide treatment and minimal residual disease monitoring
- Leverage rapid in-house testing with ever-expanding reference testing options to promote timely identification of ideal therapies
By integrating molecular testing into routine oncology practice, clinicians can match patients with therapies tailored to their tumor’s unique genetic profile. This precision approach not only enhances treatment effectiveness but also minimizes unnecessary toxicity, supporting more informed and effective cancer care decisions.